To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

How to transfigure the Wikipedia

Would you like Wikipedia to always look as professional and up-to-date? We have created a browser extension. It will enhance any encyclopedic page you visit with the magic of the WIKI 2 technology.

Try it — you can delete it anytime.

Install in 5 seconds
4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
Spanish Articles
Improved in 24 Hours
Added in 24 Hours
Languages
Recent
Show all languages
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
Great Wikipedia has got greater.
.
Leo
Newton
Brights
Milds

CD120

De Wikipedia, la enciclopedia libre

CD120 (Cruster de la diferenciación 120) puede referirse a dos miembros de la superfamilia de receptores del factor de necrosis tumoral: el receptor 1 del factor de necrosis tumoral (TNFR1) y el receptor 2 del factor de necrosis tumoral (TNFR2). [1]​ [2]​

Subtipos de receptores

Hay dos variantes del receptor, cada una codificada por un gen distinto:

  • CD120a - TNFR1 - Miembro 1A de la superfamilia TNFR
  • CD120b - TNFR2 - Miembro 1B de la superfamilia TNFR

TNFR1 es el tipo de receptor responsable de la mediación del comportamiento de enfermedad inducido por TNF-alfa [3]​ y participa en procesos neurotóxicos. [4]​ Se han encontrado niveles elevados de TNFR1 en trastornos mentales graves. [5]​

Vía de señalización

Vía de señalización del TNF -R1. Las líneas grises discontinuas representan varios pasos

Referencias

  1. ↑ Locksley RM, Killeen N, Lenardo MJ (2001). «The TNF and TNF receptor superfamilies: integrating mammalian biology». Cell 104 (4): 487-501. PMID 11239407. doi:10.1016/S0092-8674(01)00237-9. 
  2. ↑ Hehlgans T, Pfeffer K (2005). «The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games». Immunology 115 (1): 1-20. PMC 1782125. PMID 15819693. doi:10.1111/j.1365-2567.2005.02143.x. 
  3. ↑ Palin K, Bluthé RM, McCusker RH, Levade T, Moos F, Dantzer R, Kelley KW (January 2009). «The type 1 TNF receptor and its associated adapter protein, FAN, are required for TNFalpha-induced sickness behavior». Psychopharmacology 201 (4): 549-56. PMC 2711641. PMID 18825372. doi:10.1007/s00213-008-1331-4. 
  4. ↑ McCoy MK, Tansey MG (2008). «TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease». J Neuroinflammation 5 (1): 45. PMC 2577641. PMID 18925972. doi:10.1186/1742-2094-5-45. 
  5. ↑ Hope S, Melle I, Aukrust P, Steen NE, Birkenaes AB, Lorentzen S, Agartz I, Ueland T, Andreassen OA (November 2009). «Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor». Bipolar Disord 11 (7): 726-34. PMID 19839997. doi:10.1111/j.1399-5618.2009.00757.x. 

Enlaces externos

Esta página se editó por última vez el 25 abr 2024 a las 21:49.
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.
Contact WIKI 2
Introduction
Terms of Service
Privacy Policy