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Fosfomevalonato quinasa

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Fosfomevalonato quinasa
Estructuras disponibles
PDB
 Estructuras enzimáticas
RCSB PDB, PDBe, PDBsum
Identificadores
Identificadores
externos
 Bases de datos de enzimas
IntEnz: entrada en IntEnz
BRENDA: entrada en BRENDA
ExPASy: NiceZime view
KEGG: entrada en KEEG
PRIAM: perfil PRIAM
ExplorEnz: entrada en ExplorEnz
MetaCyc: vía metabólica
Número EC 2.7.4.2
PubMed (Búsqueda)
[1]


PMC (Búsqueda)
[2]
[editar datos en Wikidata]

La fosfomevalonato quinasa es una enzima (EC 2.7.4.2) en la ruta del mevalonato que en los humanos está codificada por el gen PMVK.[1]​[2]​[3]​ Cataliza la reacción:

ATP + (R)-5-Fosfomevalonato <=> ADP + (R)-5-Difosfomevalonato

Ruta del Mevalonato

Referencias

  1. ↑ «Mevalonic acid pyrophosphate and isopentenylpyrophosphate». The Journal of Biological Chemistry 234: 2595-604. October 1959. PMID 13801508. 
  2. ↑ «Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase». Archives of Biochemistry and Biophysics 83 (1): 259-67. July 1959. PMID 13662013. doi:10.1016/0003-9861(59)90031-1. 
  3. ↑ «Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver». The Biochemical Journal 75: 417-28. June 1960. PMC 1204488. PMID 14416398. doi:10.1042/bj0750417. 
Esta página se editó por última vez el 19 ago 2021 a las 22:44.
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