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Plakohipaforina

De Wikipedia, la enciclopedia libre

Las Plakohipaforinas son indolaminas que contienen yodo. Son nombradas por su semejanza química con la hipaforina.[1][2]​ Fueron reportadas por primera vez por ser aislada de la esponja caribeña Plakortis simplex en 2003, plakohipaforinas A-C Las Plakohipaforinas D-F, también encontradas P. simplex, fueron reportadas en 2004.

Plakohipaforina Nombre Fórmula química SMILES Imagen
Plakohipaforina 7-Yodo-N,N,N-trimetiltriptófano C14H17IN2O2 OC(=O)C(N(C)(C)C)Cc2cnc1c2cccc1I
Plakohipaforina A
Plakohipaforina B 6,7-Diyodo-N,N,N-trimetiltriptófano C14H16I2N2O2 OC(=O)C(N(C)(C)C)Cc2cnc1c2ccc(I)c1I
Plakohipaforina B
Plakohipaforina C 5,7-Diyodo-N,N,N-trimetiltriptófano C14H16I2N2O2 CN(C)(C)C(C(=O)O)Cc2cnc1c2cc(I)cc1I
Plakohipaforina C
Plakohipaforina D 5,6-Diyodo-N,N,N-trimetiltriptófano C14H16I2N2O2 Ic2cc1c(cc2I)ncc1CC(C(O)=O)N(C)(C)C
Plakohipaforina D
Plakohipaforina E 5,6,7-Triyodo-N,N,N-trimetiltriptófano C14H15I3N2O2 CN(C)(C)C(C(=O)O)Cc1cnc(c(I)c2I)c1cc2I
Plakohipaforina E
Plakohipaforina F 6-Cloro-5-yodo-N,N,N-trimetiltriptófano C14H16ClIN2O2 Clc2c1ncc(CC(C(O)=O)N(C)(C)C)c1cc(I)c2
Plakohipaforina F

Referencias

  1. Borrelli, Francesca, et al., 2003. Plakohypaphorines A-C, Iodine-Containing Alkaloids from the Caribbean Sponge Plakortis simplex. European Journal of Organic Chemistry. 2003(2), pp. 284-287.
  2. Borrelli, Francesca, et al., 2004. Iodinated Indole Alkaloids From Plakortis simplex, New Plakohypaphorines and an Evaluation of Their Antihistamine Activity. European Journal of Organic Chemistry. 2004(15), pp. 3227-3232.
Esta página se editó por última vez el 23 oct 2019 a las 11:56.
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